Postby loremaster » 10 Aug 2009 04:16
Hahaha. Nice.
Just for clarification, protein "Fold Space" is, if i remember, a sort of pun on the concept of "phase space". It is a way of expressing all the many ways proteins do and do not fold (as in, peptide chains bending to come into contact and form different shapes, NOT bending spacetime). It is i think supposed to be of some practical use in tracking the common ancestry of proteins, as well as grouping them, and understanding protein post-translational modifications. It includes things like formation of chains, and sheets, particular configuration of protein domains and their folding. It's also useful for identifying mis-folding proteins, and observing particular sequences important in producing certain folds (e.g. we need a Methionine in position 3....., cysteine in position 8 etc)
The HLP hasnt released Frank's notes yet, Brian hasn't got the handwriting quite right!